Low-dimensional encoding of decisions in parietal cortex reflects long-term training history.

ABSTRACT: Neurons in parietal cortex exhibit task-related activity during decision-making tasks. However, it remains unclear how long-term training to perform different tasks over months or even years shapes neural computations and representations. We examine lateral intraparietal area (LIP) responses during a visual motion delayed-match-to-category task. We consider two pairs of male macaque monkeys with different training histories: one trained only on the categorization task, and another first trained to perform fine motion-direction discrimination (i.e., pretrained). We introduce a novel analytical approach-generalized multilinear models-to quantify low-dimensional, task-relevant components in population activity. During the categorization task, we found stronger cosine-like motion-direction tun

SUBMITTER: Latimer KW 

PROVIDER: S-EPMC9950136 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature