Ensuring Superior Reporting of Radiation Therapy Noninferiority Trials: A Systematic Review.

ABSTRACT:

Purpose

Although the frequency of noninferiority trials is increasing, the consistency of the reporting of these trials can vary. The aim of this systematic review was to assess the reporting quality of radiation therapy noninferiority trials.

Methods and materials

The PubMed, Embase, and Cochrane databases were queried for randomized controlled radiation therapy trials with noninferiority hypotheses published in English between January 2000 and July 2022, and this was performed by an information scientist. Descriptive statistics were used to summarize data.

Results

Of 423 records screened, 59 (14%) were included after full-text review. All were published after 2003 and open label. The most common primary cancer type was breast (n = 15, 25%). Altered radiation fractio

SUBMITTER: Arifin AJ 

PROVIDER: S-EPMC9958349 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature