Dataset Information

Associations between Oral Human Herpesvirus-6 and -7 and Periodontal Conditions in Older Adults.

ABSTRACT:

Background

The associations between oral human herpesvirus-6 (HHV-6) and HHV-7, periodontal conditions, and lifestyle-related diseases, such as hypertension, diabetes, and dyslipidemia, have not been fully investigated in older adults.

Methods

Seventy-four older patients who visited Hiroshima University Hospital were enrolled. Tongue swab samples were employed, and a real-time polymerase chain reaction was performed to detect HHV-6 and HHV-7 DNA. Dental plaque accumulation, probing pocket depth, and bleeding on probing (BOP) (i.e., a sign of periodontal inflammation) were examined. The periodontal inflamed surface area (PISA) value (i.e., an indicator of the severity of periodontitis) was also examined.

Results

Of the 74 participants, one participant (1.4%) was HHV-6 DNA-positive and 36 participants (48.6%) were HHV-7 DNA-positive. A significant association between HHV-7 DNA and probing depth was found (p = 0.04). The HHV-7 DNA-positive participants had a higher positive rate of a ≥6-mm periodontal pocket with BOP (25.0%) than the HHV-7 DNA-negative participants (7.9%). Additionally, the HHV-7 DNA-positive participants had a higher PISA value than the HHV-7 DNA-negative participants. However, there was no significant association between HHV-7 and the PISA value (p = 0.82). No significant association was found between HHV-7 and lifestyle-related diseases (p > 0.05).

Conclusions

Oral HHV-7 infection is associated with a deep periodontal pocket.

SUBMITTER: Hamada N

PROVIDER: S-EPMC9965650 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Publications

Associations between Oral Human Herpesvirus-6 and -7 and Periodontal Conditions in Older Adults.

Hamada Natsuki N Shigeishi Hideo H Oka Iori I Sasaki Mio M Kitasaki Honami H Nakamura Mariko M Yano Kanako K Wu Chia-Hsin CH Kaneyasu Yoshino Y Maehara Tomoko T Sugiyama Masaru M Ohta Kouji K

Life (Basel, Switzerland) 20230123 2

<h4>Background</h4>The associations between oral human herpesvirus-6 (HHV-6) and HHV-7, periodontal conditions, and lifestyle-related diseases, such as hypertension, diabetes, and dyslipidemia, have not been fully investigated in older adults.<h4>Methods</h4>Seventy-four older patients who visited Hiroshima University Hospital were enrolled. Tongue swab samples were employed, and a real-time polymerase chain reaction was performed to detect HHV-6 and HHV-7 DNA. Dental plaque accumulation, probin ...[more]

PMID: 36836681

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Dataset Information

Associations between Oral Human Herpesvirus-6 and -7 and Periodontal Conditions in Older Adults.

Background

Methods

Results

Conclusions

Publications

Associations between Oral Human Herpesvirus-6 and -7 and Periodontal Conditions in Older Adults.

Similar Datasets

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