Alteration of brain network centrality in CTN patients after a single triggering pain.

ABSTRACT:

Objective

The central nervous system may also be involved in the pathogenesis of classical trigeminal neuralgia (CTN). The present study aimed to explore the characteristics of static degree centrality (sDC) and dynamic degree centrality (dDC) at multiple time points after a single triggering pain in CTN patients.

Materials and methods

A total of 43 CTN patients underwent resting-state function magnetic resonance imaging (rs-fMRI) before triggering pain (baseline), within 5 s after triggering pain (triggering-5 s), and 30 min after triggering pain (triggering-30 min). Voxel-based degree centrality (DC) was used to assess the alteration of functional connection at different time points.

Results

The sDC values of the right caudate nucleus, fusiform gyrus, middle tempora

SUBMITTER: Ge X 

PROVIDER: S-EPMC9978223 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature