Association of serum PUFA and linear growth over 12 months among 6-10 years old Ugandan children with or without HIV.

ABSTRACT:

Objective

To quantify PUFA-associated improvement in linear growth among children aged 6-10 years.

Design

Serum fatty acids (FA), including essential FA (EFA) (linoleic acid (LA) and α-linolenic acid (ALA)) were quantified at baseline using GC-MS technology. FA totals by class (n-3, n-6, n-9, PUFA and SFA) and FA ratios were calculated. Height-for-age Z-score (HAZ) relative to WHO population reference values were calculated longitudinally at baseline, 6 and 12 months. Linear regression models estimated PUFA, HIV status and their interaction-associated standardised mean difference (SMD) and 95 % CI in HAZ over 12 months.

Setting

Community controls and children connected to community health centre in Kampala, Uganda, were enrolled.

Participants

Children perinatal

SUBMITTER: Pobee RA 

PROVIDER: S-EPMC9991724 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature