Survival after resection of brain metastasis: impact of synchronous versus metachronous metastatic disease.

ABSTRACT:

Purpose

Patients with brain metastasis (BM) from solid tumors are in an advanced stage of cancer. BM may occur during a known oncological disease (metachronous BM) or be the primary manifestation of previously unknown cancer (synchronous BM). The time of diagnosis might decisively impact patient prognosis and further treatment stratification. In the present study, we analyzed the prognostic impact of synchronous versus (vs.) metachronous BM occurrence following resection of BM.

Methods

Between 2013 and 2018, 353 patients had undergone surgical therapy for BM at the authors' neuro-oncological center. Survival stratification calculated from the day of neurosurgical resection was performed for synchronous vs. metachronous BM diagnosis.

Results

Non-small-cell lung carcino

SUBMITTER: Potthoff AL 

PROVIDER: S-EPMC9992001 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature