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Crystal structures of 4-[(4-methylbenzyl)oxy]benzohydrazide and its N′-[(thiophen-2-yl)methylidene]- derivative

ABSTRACT: The crystal and molecular structures of a benzoylhydrazine bearing an ether group and of its N′-[(thiophen-2-yl)methylidene derivative are reported and compared. The molecular and crystal structures of a benzoylhydrazine bearing an ether group, 4-[(4-methylbenzyl)oxy]benzohydrazide, C15H16N2O2, (I), and of the corresponding N′-[(thiophen-2-yl)methylidene]- derivative, 4-[(4-methylbenzyl)oxy]-N′-[(thiophen-2-yl)methylidene]benzohydrazide, C20H18N2O2S, (II), are described. The supramolecular structures of both compounds are governed by N—H⋯N and N—H⋯O hydrogen-bonding interactions. The hydrazine compound (I) shows a crystal packing with a more complex hydrogen-bonding scheme because of the NH—NH2 entity, forming a di-periodic supramolecular structure extending parallel to (100). Hydrazone molecules in (II) are hydrogen-bonded through N—H⋯O interactions, giving rise to the formation of ribbons parallel to [010]. Molecules of (I) and (II) show a different orientation of the carbohydrazide moiety likely to favor the crystal packing and thus hydrogen-bonding interactions.

SUBMITTER: Banna M

PROVIDER: S-EPMC9993917 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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