Principled, practical, flexible, fast: a new approach to phylogenetic factor analysis.

ABSTRACT: Biological phenotypes are products of complex evolutionary processes in which selective forces influence multiple biological trait measurements in unknown ways. Phylogenetic comparative methods seek to disentangle these relationships across the evolutionary history of a group of organisms. Unfortunately, most existing methods fail to accommodate high-dimensional data with dozens or even thousands of observations per taxon. Phylogenetic factor analysis offers a solution to the challenge of dimensionality. However, scientists seeking to employ this modeling framework confront numerous modeling and implementation decisions, the details of which pose computational and replicability challenges.We develop new inference techniques that increase both the computational efficiency and modeling flexi

SUBMITTER: Hassler GW 

PROVIDER: S-EPMC9997680 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature