Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and older adults.
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ABSTRACT:
SUBMITTER: Min J
PROVIDER: S-EPMC9998394 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Publications
Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and older adults.
Min Jungwon J Rouanet Jeremy J Martini Alessandra Cadete AC Nashiro Kaoru K Yoo Hyun Joo HJ Porat Shai S Cho Christine C Wan Junxiang J Cole Steve W SW Head Elizabeth E Nation Daniel A DA Thayer Julian F JF Mather Mara M
Scientific reports 20230309 1
Slow paced breathing via heart rate variability (HRV) biofeedback stimulates vagus-nerve pathways that counter noradrenergic stress and arousal pathways that can influence production and clearance of Alzheimer's disease (AD)-related proteins. Thus, we examined whether HRV biofeedback intervention affects plasma Αβ40, Αβ42, total tau (tTau), and phosphorylated tau-181 (pTau-181) levels. We randomized healthy adults (N = 108) to use slow-paced breathing with HRV biofeedback to increase heart rate ...[more]
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