Dataset Information
Taf15 amyloid filaments - Individual 2
Ontology highlight
ABSTRACT:
SUBMITTER: Benjamin Ryskeldi-Falcon
PROVIDER: EMPIAR-11737 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature 20231206 7994
Frontotemporal lobar degeneration (FTLD) causes frontotemporal dementia (FTD), the most common form of dementia after Alzheimer's disease, and is often also associated with motor disorders<sup>1</sup>. The pathological hallmarks of FTLD are neuronal inclusions of specific, abnormally assembled proteins<sup>2</sup>. In the majority of cases the inclusions contain amyloid filament assemblies of TAR DNA-binding protein 43 (TDP-43) or tau, with distinct filament structures characterizing different F ...[more]
