Dataset Information
Motion corrected micrographs
Ontology highlight
ABSTRACT:
SUBMITTER: Anna Sundborger-Lunna
PROVIDER: EMPIAR-12470 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers.
Communications biology 20250205 1
Bin/Amphiphysin/Rvs167 (BAR) domain containing proteins are peripheral membrane proteins that regulate intracellular membrane curvature. BAR protein endophilin B1 plays a key role in multiple cellular processes critical for oncogenesis, including autophagy and apoptosis. Amphipathic regions in endophilin B1 drive membrane association and tubulation through membrane scaffolding. Our understanding of exactly how BAR proteins like endophilin B1 promote highly diverse intracellular membrane remodeli ...[more]