The Precision Oncology Approach to Molecular Cancer Therapeutics Targeting Oncogenic Signaling Pathways is a Means to an End

ABSTRACT: Cancer is a fatal genetic disease with different aspects of complexity, including cancer immune evasion, treatment resistance and recurrence, requiring optimized treatment for proper cure. Molecular studies have revealed that tumors are hugely heterogeneous in nature, leading to the complexity of cancer progression that is ultimately linked to its genetic machinery. In recent decades, there has been a deluge in the large-scale production of anticancer agents, primarily due to advances in genomic technologies enabling precise targeting of oncogenic pathways involved in disease development. It is important to note that patients with the same types of cancer respond differently to cancer treatments, indicating the need for patient-specific treatment options. An in-depth genomic study of tumor

ORGANISM(S): Homo sapiens (human)

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PROVIDER: S-BSST1331 | biostudies-other |

SECONDARY ACCESSION(S): https://dataverse.harvard.edu/dataset.xhtml?persistentId=doi:10.7910/DVN/MQHWUC

REPOSITORIES: biostudies-other