Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

[CMP] [cell line] [SIDM01621] Acute Myeloid Leukemia

ABSTRACT:

SUBMITTER:

PROVIDER: S-CMO1446 | biostudies-other |

REPOSITORIES: biostudies-other

ACCESS DATA

Json Xml

Similar Datasets

Immunopeptidome of an acute myeloid leukemia cell line THP1

Project description:We report the use of complementary peptide antigen enrichment and comprehensive mass spectrometric acquisition strategies to provide in-depth immunopeptidome data for AML cell line THP1

2021-07-09 | MSV000087786 | MassIVE

Immunopeptidome of an acute myeloid leukemia cell line THP1

2020-05-13 | PXD015039 | Pride

Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles.

Project description: Not available

| S-EPMC8699161 | biostudies-literature

Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line.

Project description: Not available

| S-EPMC9465881 | biostudies-literature

An iPSC line derived from a human acute myeloid leukemia cell line (HL-60-iPSC) retains leukemic abnormalities and displays myeloid differentiation defects.

Project description: Not available

| S-EPMC8031422 | biostudies-literature

Acute myeloid leukemia cell line RNA-Seq

Project description:We performed RNA-Seq on acute promyelocytic leukemia (APL) cells treated with both all-trans retinoic acid (ATRA) and trichostatin A (TSA) to identify transcriptional changes potentially associated with changes in APL cell mechanical properties. As a control, we performed the same treatments and RNA-Seq analysis on HL-60 cells, which were derived from a patient diagnosed with APL but whose cells lacked the hallmark fusion gene associated with APL. We performed RNA-Seq on these three cell lines (AP-1060, NB4, HL-60) under different conditions (untreated, TSA, ATRA, TSA + ATRA), and identified differentially expressed genes between samples and conditions. This study identified differentially expressed genes and enriched gene sets associated with (1) a resistance to differentiation induced by ATRA or (2) changes in mechanical properties. Overall, we find evidence that ATRA resistance and mechanical properties may be linked by the degree of chromatin condensation in APL cells.

2021-05-26 | GSE175507 | GEO