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A circular-dichroism study of epidermolytic toxins A and B from Staphylococcus aureus.

ABSTRACT: The far-u.v. circular-dichroism spectra of the two epidermolytic toxins was analysed into fractional contributions of 0.09 helix and 0.46 beta-sheet to each toxin structure. Trifluoroethanol perturbation caused an initial increase in dichroic absorption at 205 nm and then a change characterized as a beta-sheet-to-alpha-helix transition. The intense near-u.v. spectra suggested that the toxins have unusually rigid, though different, aromatic-side-chain arrangements.

SUBMITTER: Bailey CJ 

PROVIDER: S-EPMC1158295 | biostudies-other | 1982 Jun

REPOSITORIES: biostudies-other

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