Ontology highlight
ABSTRACT:
SUBMITTER: Hirata D
PROVIDER: S-EPMC1170415 | biostudies-other | 1998 Feb
REPOSITORIES: biostudies-other
Hirata D D Masuda H H Eddison M M Toda T T
The EMBO journal 19980201 3
The main structural components of microtubules are alpha- and beta-tubulins. A group of proteins called cofactors are crucial in the formation of assembly-competent tubulin molecules in vitro. Whilst an in vitro role is emerging for these cofactors, their biological functions in vivo remain to be established. In order to understand the fundamental mechanisms that determine cell polarity, we have screened for fission yeast mutants with altered polarity. Here we show that alp1+ encodes a homologue ...[more]