Ontology highlight
ABSTRACT:
SUBMITTER: Jones TR
PROVIDER: S-EPMC189296 | biostudies-other | 1995 Aug
REPOSITORIES: biostudies-other
Journal of virology 19950801 8
Reduction of major histocompatibility complex class I cell surface expression occurs in adenovirus-, herpes simplex virus-, human cytomegalovirus (HCMV)-, and murine cytomegalovirus-infected cell systems. Recently, it was demonstrated that the down-regulation mediated by HCMV infection is posttranslational, as a result of increased turnover of class I heavy chains in the endoplasmic reticulum (M. F. C. Beersma, M. J. E. Bijlmakers, and H. L. Ploegh, J. Immunol. 151:4455-4464, 1993; Y. Yamashita, ...[more]