Ontology highlight
ABSTRACT:
SUBMITTER: Leiden JM
PROVIDER: S-EPMC241465 | biostudies-other | 1992 Oct
REPOSITORIES: biostudies-other
Journal of virology 19921001 10
Human immunodeficiency virus type 1 (HIV-1) and HIV-2 are structurally related retroviruses which both cause AIDS in humans. Although both viruses establish latency in quiescent human-peripheral-blood T cells, the asymptomatic phase of HIV-2 infection may be more prolonged than that of HIV-1. The latent phases of both HIV-1 and HIV-2 infection have been shown to be disrupted by T-cell activation, a process that requires host cell transcription factors. In the case of HIV-1, the transcription fac ...[more]