Ontology highlight
ABSTRACT:
SUBMITTER: Ebihara H
PROVIDER: S-EPMC3532827 | biostudies-other | 2013 Jan
REPOSITORIES: biostudies-other
The Journal of infectious diseases 20121008 2
Ebola hemorrhagic fever (EHF) is a severe viral infection for which no effective treatment or vaccine is currently available. While the nonhuman primate (NHP) model is used for final evaluation of experimental vaccines and therapeutic efficacy, rodent models have been widely used in ebolavirus research because of their convenience. However, the validity of rodent models has been questioned given their low predictive value for efficacy testing of vaccines and therapeutics, a result of the inconsi ...[more]