Ontology highlight
ABSTRACT:
SUBMITTER: Vestentoft PS
PROVIDER: S-EPMC3892118 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Fibrogenesis & tissue repair 20131220 1
<h4>Background</h4>Tissue repair in the adult mammalian liver occurs in two distinct processes, referred to as the first and second tiers of defense. We undertook to characterize the changes in molecular constituents of the extracellular matrix when hepatic progenitor cells (HPCs) respond in a second tier of defense to liver injury.<h4>Results</h4>We used transcriptional profiling on rat livers responding by a first tier (surgical removal of 70% of the liver mass (PHx protocol)) and a second tie ...[more]