Ontology highlight
ABSTRACT:
SUBMITTER: Sugimoto A
PROVIDER: S-EPMC394535 | biostudies-other | 1995 Sep
REPOSITORIES: biostudies-other
Sugimoto A A Hozak R R RR Nakashima T T Nishimoto T T Rothman J H JH
The EMBO journal 19950901 18
Programmed cell death (apoptosis) is a normally occurring process used to eliminate unnecessary or potentially harmful cells in multicellular organisms. Recent studies demonstrate that the molecular control of this process is conserved phylogenetically in animals. The dad-1 gene, which encodes a novel 113 amino acid protein, was originally identified in a mutant hamster cell line (tsBN7) that undergoes apoptosis at restrictive temperature. We have identified a dad-1 homologue in Caenorhabditis e ...[more]