Ontology highlight
ABSTRACT:
SUBMITTER: Sundermeier TR
PROVIDER: S-EPMC4172207 | biostudies-other | 2014 Sep
REPOSITORIES: biostudies-other
Sundermeier Thomas R TR Jin Hui H Kleinjan Matthew L ML Mustafi Debarshi D Licatalosi Donny D DD Palczewski Krzysztof K
Biochemistry 20140915 37
Mounting evidence points to roles for miRNA gene regulation in promoting development, function, and cell survival in the mammalian retina. However, little is known regarding which retinal genes are targets of miRNAs. Here, we employed a systematic, nonbiased, biochemical approach to identify targets of miRNA gene regulation in the bovine retina, a common model species for vision research. Using Argonaute high-throughput sequencing of RNAs isolated by cross-linking immunoprecipitation analysis, w ...[more]