Ontology highlight
ABSTRACT:
SUBMITTER: Noroxe DS
PROVIDER: S-EPMC5419216 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Nørøxe Dorte Schou DS Poulsen Hans Skovgaard HS Lassen Ulrik U
ESMO open 20160101 6
Despite decades of intense research, the complex biology of glioblastoma (GBM) is not completely understood. Progression-free survival and overall survival have remained unchanged since the implementation of the STUPP regimen in 2005 with concomitant radio-/chemotherapy and adjuvant chemotherapy with temozolomide. In the context of Hanahan and Weinberg's six hallmarks and two emerging hallmarks of cancer, we discuss up-to-date status and recent research in the biology of GBM. We discuss the clin ...[more]