The persistence of a silent memory.

ABSTRACT: One of the most striking properties of RNA interference (RNAi) in Caenorhabditis elegans is its persistence in offspring after the triggering double-stranded RNA (dsRNA) has disappeared. A new study reveals that a heterochromatic silencing mark is deposited around the targets of RNAi and is transmitted through generations. These results show that RNAi can induce stable and heritable chromatin modifications in animals.

SUBMITTER: Zaratiegui M 

PROVIDER: S-EPMC5556923 | biostudies-other | 2012 Jan

REPOSITORIES: biostudies-other