Ontology highlight
ABSTRACT:
SUBMITTER: McCauley KB
PROVIDER: S-EPMC5995784 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Stem cell reports 20180412 5
Lung epithelial lineages have been difficult to maintain in pure form in vitro, and lineage-specific reporters have proven invaluable for monitoring their emergence from cultured pluripotent stem cells (PSCs). However, reporter constructs for tracking proximal airway lineages generated from PSCs have not been previously available, limiting the characterization of these cells. Here, we engineer mouse and human PSC lines carrying airway secretory lineage reporters that facilitate the tracking, pur ...[more]