Ontology highlight
ABSTRACT:
SUBMITTER: Sokolova M
PROVIDER: S-EPMC6214840 | biostudies-other | 2018 Oct
REPOSITORIES: biostudies-other
iScience 20181015
Actin has been linked to processes spanning the whole gene expression cascade, from regulating specific transcription factors, such as myocardin-related transcription factor, to chromatin remodeling and RNA polymerase function. However, whether actin controls the transcription of only specific genes or has a global role in gene expression has remained elusive. Our genome-wide analysis reveals, for the first time, that actin interacts with essentially all transcribed genes in Drosophila ovaries. ...[more]