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Two new lanostane triterpenoids from the branches and leaves of Polyalthia oblique.


ABSTRACT: Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15?-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6?-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.

SUBMITTER: Wang LK 

PROVIDER: S-EPMC6271888 | biostudies-other | 2014

REPOSITORIES: biostudies-other

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Two new lanostane triterpenoids from the branches and leaves of Polyalthia oblique.

Wang Liu-Kai LK   Zheng Cai-Juan CJ   Li Xiao-Bao XB   Chen Guang-Ying GY   Han Chang-Ri CR   Chen Wen-Hao WH   Song Xiao-Ping XP  

Molecules (Basel, Switzerland) 20140606 6


Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new  ...[more]

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