Ontology highlight
ABSTRACT:
SUBMITTER: Bhukel A
PROVIDER: S-EPMC6428838 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Nature communications 20190321 1
Macroautophagy is an evolutionarily conserved cellular maintenance program, meant to protect the brain from premature aging and neurodegeneration. How neuronal autophagy, usually loosing efficacy with age, intersects with neuronal processes mediating brain maintenance remains to be explored. Here, we show that impairing autophagy in the Drosophila learning center (mushroom body, MB) but not in other brain regions triggered changes normally restricted to aged brains: impaired associative olfactor ...[more]