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First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours

ABSTRACT: The goal of this clinical trial is to learn if the OATD-02 administration (orally) in monotherapy is safe and has the pharmacodynamic potential to restore and enhance tumour responses to immunotherapy through increased arginine levels or intrinsic anti-tumour activity in participants with advanced metastatic colorectal cancer, ovarian cancer, renal cancer or pancreatic cancer.

DISEASE(S): Carcinoma,Advanced Ovarian Carcinoma,Metastatic Ovarian Carcinoma,Metastatic Colorectal Carcinoma,Advanced Colorectal Carcinoma,Colorectal Cancer,Pancreatic Cancer,Metastatic Renal Cell Carcinoma,Advanced Renal Cell Carcinoma,Ovarian Cancer,Advanced Pancreatic Carcinoma,Metastatic Pancreatic Carcinoma,Carcinoma, Ovarian Epithelial,Carcinoma, Renal Cell,Colorectal Neoplasms,Ovarian Neoplasms,Pancreatic Neoplasms,Solid Tumors

PROVIDER: 10788 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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