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A Trial of CXD101 in Combination With Nivolumab in Patients With Metastatic Microsatellite-Stable Colorectal Cancer


ABSTRACT: This is a study to assess the safety and efficacy of CXD101 in combination with the PD-1 Inhibitor Nivolumab in patients with metastatic, previously-treated, Microsatellite-Stable (MSS) Colorectal Carcinoma (CRC). The primary hypothesis of this study is that CXD101 and anti-PD1 monoclonal antibody synergise the anti-tumour activity in MSS colorectal cancer patients (~95% of CRC) who do not seem to respond to anti-PD1 or -PD-L1 immunotherapy alone.

DISEASE(S): Colorectal Carcinoma,Colorectal Neoplasms Malignant,Colorectal Cancer Metastatic,Colorectal Neoplasms,Metastatic, Previously-treated, Microsatellite-stable Colorectal Carcinoma,Neoplasms

PROVIDER: 2308907 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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