Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ena-DATASET-UMCG-30-03-2016-15:47:18:846-27 - samples

ABSTRACT: Meta-genomic sequencing of 1,200 LifeLines-DEEP participants

PROVIDER: EGAD00001001991 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Json Xml

Similar Datasets

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells.

Project description: Not available

| S-EPMC6612093 | biostudies-literature

The 15-min Subcellular Proteome

Project description:This project integrated data-independent acquisition (DIA) with capillary electrophoresis electrospray ionization mass spectrometry (CE-ESI-MS) to enable fast single-cell proteomics. With <15 min of effective separation time in a bottom-up proteomics setting, this technology returned ~1,200 proteins from a single HeLa-cell-equivalent proteome amount. Furthermore, using capillary microsampling to collect the proteome from identified cells in a cleavage-stage embryo of the vertebrate Xenopus laevis (frog) embryo, ~1,400 proteins were identified by measuring ~5 ng of the subcellular proteome content aspirated from live Xenopus embryos. CE-ESI-MS with DIA enhanced proteome detection sensitivity and improved analytical throughput.

2024-09-27 | PXD046467 | Pride

Staphylococcus aureus isolate:30-47

Project description:Staphylococcus aureus isolate:30-47 Genome sequencing and assembly

| PRJNA471840 | ENA

LifeLines-DEEP population multi-omix cohort from the noth of the Netherlands.

Project description:The LifeLines-DEEP cohort is a sub-cohort of the LifeLines cohort (167,729 participants) that employs a broad range of investigative procedures to assess the biomedical, socio-demographic, behavioral, physical and psychological factors that contribute to health and disease in the general Dutch population, (Scholtens 2015). A subset of approximately 1,500 participants also took part in LifeLines-DEEP. For these participants, additional biological materials were collected, including analysis of the gut microbiome composition. The phenotyping and processing of LifeLines-DEEP has been described in Tigchelaar (2015).

| EGAS00001001704 | EGA

AOUP-UMCG-mcr1.2

Project description:AOUP-UMCG-mcr1.2

| PRJEB25114 | ENA

ena-DATASET-UMCG-19-07-2017-11:33:37:421-106 - samples

Project description:16S sequencing of stool samples of LifeLines-DEEP, domain V4

| EGAD00001003453 | EGA

Abstracts of scientific contributions to GCOM 2019 : Berlin, Germany. 27 - 30 March 2019

Project description: Not available

| S-EPMC6699080 | biostudies-literature

Project description: Not available

| S-EPMC10756369 | biostudies-literature

Regulation of nuclear gene expression by PK 11195, a ligand specific for the mitochondrial 18 kDa translocator protein (TSPO) (15, 30, and 45 minutes of exposure)

Project description:It is known that application of TSPO ligands as well as knockdown of the mitochondrial 18 kDa translocator protein (TSPO) modulate viability, proliferation, adhesion, and migration of glioblastoma cells, as well as angiogenesis. To study the ability of the TSPO to regulate gene expression in relation to these functions we applied microarray analysis of gene expression to U118MG glioblastoma cells. Seen at the time points of 15, 30, and 45 minutes, the TSPO ligand PK 11195 induced changes in expression of immediate early genes and transcription factors. These changes also included gene products that are part of the canonical pathway for modulation of general gene expression. These changes peaked at 30 minutes. Thus, it appears that the TSPO is part of the retrograde mitochondrial-nuclear signaling pathway for modulation of gene expression. Consequently, our data indicate that this is a major venue whereby TSPO may drive its numerous functional effects. Keywords: modulation of nuclear gene expression, mitochondrial 18 kDa translocator protein (TSPO), TSPO ligand, PK 11195, 2-Cl-MGV-1, retrograde mitochondrial-nuclear signaling pathway, microscopy, mitochondria, cell nucleus abstract of annual meetingof the israel society for neuroscience, section B, abstract # 98.

2016-08-17 | GSE85697 | GEO

Test-retest reliability of the 30-15 Intermittent Fitness Test: A systematic review.

Project description: Not available

| S-EPMC8343059 | biostudies-literature