Other

Dataset Information

1K

Hospital Clinic Barcelona

ABSTRACT: Organisation EGAO00000000023

PROVIDER: EGAO00000000023 | EGA |

REPOSITORIES: EGA

Json Xml
altmetric image

Publications

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.

Puente Xose S XS   Pinyol Magda M   Quesada Víctor V   Conde Laura L   Ordóñez Gonzalo R GR   Villamor Neus N   Escaramis Georgia G   Jares Pedro P   Beà Sílvia S   González-Díaz Marcos M   Bassaganyas Laia L   Baumann Tycho T   Juan Manel M   López-Guerra Mónica M   Colomer Dolors D   Tubío José M C JM   López Cristina C   Navarro Alba A   Tornador Cristian C   Aymerich Marta M   Rozman María M   Hernández Jesús M JM   Puente Diana A DA   Freije José M P JM   Velasco Gloria G   Gutiérrez-Fernández Ana A   Costa Dolors D   Carrió Anna A   Guijarro Sara S   Enjuanes Anna A   Hernández Lluís L   Yagüe Jordi J   Nicolás Pilar P   Romeo-Casabona Carlos M CM   Himmelbauer Heinz H   Castillo Ester E   Dohm Juliane C JC   de Sanjosé Silvia S   Piris Miguel A MA   de Alava Enrique E   San Miguel Jesús J   Royo Romina R   Gelpí Josep L JL   Torrents David D   Orozco Modesto M   Pisano David G DG   Valencia Alfonso A   Guigó Roderic R   Bayés Mónica M   Heath Simon S   Gut Marta M   Klatt Peter P   Marshall John J   Raine Keiran K   Stebbings Lucy A LA   Futreal P Andrew PA   Stratton Michael R MR   Campbell Peter J PJ   Gut Ivo I   López-Guillermo Armando A   Estivill Xavier X   Montserrat Emili E   López-Otín Carlos C   Campo Elías E  

Nature 20110605 7354

Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in adults in Western countries, is a heterogeneous disease with variable clinical presentation and evolution. Two major molecular subtypes can be distinguished, characterized respectively by a high or low number of somatic hypermutations in the variable region of immunoglobulin genes. The molecular changes leading to the pathogenesis of the disease are still poorly understood. Here we performed whole-genome sequencing of four cases  ...[more]

PMID: 21642962

Publication: 1/3

Similar Datasets

Other Hospital Clinic, IDIBAPS, CIBERER
| EGAO00000000437 | EGA
Other Hospital Sant Joan de Deu, Barcelona
| EGAO00000000258 | EGA
Other Hospital St Joan de Déu, Barcelona
| EGAO00000000251 | EGA
Other Mayo Clinic
| EGAO00000000262 | EGA
Other Neuromuscular Unit. Neuropaediatrics Department. Hospital Sant Joan de Déu Barcelona
| EGAO00000000388 | EGA
Unknown Adjuvant sorafenib after heptectomy for Barcelona Clinic Liver Cancer-stage C hepatocellular carcinoma patients.
| S-EPMC4910659 | biostudies-literature
Other Biochemical, Genetics & Rett Unit, Laboratory Department, Hospital Sant Joan de Déu Barcelona,
| EGAO00000000387 | EGA
Unknown A New Treatment-integrated Prognostic Nomogram of the Barcelona Clinic Liver Cancer System for Hepatocellular Carcinoma.
| S-EPMC5554253 | biostudies-other
Unknown Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma.
| S-EPMC6107203 | biostudies-literature
Unknown New idea for treatment strategies for Barcelona Clinic Liver Cancer stages based on a network meta-analysis.
| S-EPMC5440153 | biostudies-literature