Diverse modes of genomic alterations in hepatocellular carcinoma

ABSTRACT: Hepatocellular carcinoma is the most prevalent type of liver cancer. We intended to study the genomic landscape of this disease. We conducted whole-genome, exome and transcriptome sequencing for 42 patients. We show diverse modes in which the HCC genome is affected in these patients, including well-known and novel mutations, structural variations, and Hepatitis B-virus integration into the genome.

PROVIDER: EGAS00001000824 | EGA |

REPOSITORIES: EGA