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DNA and RNA sequencing data from Ovarian Carcinosarcoma patients from the Glasgow Cohort.

ABSTRACT: In this study, we analysed DNA and RNA sequencing data from Ovarian Carcinosarcoma patients, from isolated carcinoma and sarcoma components and investigated DNA variants as well as gene expression. Genomic analyses from this data and further investigation from preclinical models of ovarian carcinosarcoma support the conversion theory for disease development and indicate that microtubule inhibitors could be used to suppress EMT and stimulate anti-tumour immunity.

PROVIDER: EGAS00001006605 | EGA |

REPOSITORIES: EGA

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