Whole genome sequencing of AVM endothelial and non-endothelial cell fractions

ABSTRACT: We previously identified somatic activating KRAS mutations in a majority of human arteriovenous malformations (AVMs), using whole exome sequencing, which were enhanced in AVM endothelial cell fractions. We have now performed whole genome sequencing on AVM endothelial and non-endothelial cell fractions, as well as paired blood samples, in order to identify further somatic mutations.

PROVIDER: EGAS00001006719 | EGA |

REPOSITORIES: EGA