Genomics

Dataset Information

0

The HIV co-receptor CCR5, regulates the cellular architecture of osteoclast


ABSTRACT: C-C chemokine receptor 5 (CCR5) is a co-receptor of HIV. Its ligand, CCL5 significantly augmented the number of wild-type osteoclasts but not Ccr5-deficient cells, indicating that CCL5 enhanced RANKL-induced osteoclastogenesis through CCR5. To investigate the changes in the transcriptional signatures induced by CCL5 in osteoclastogenesis, cultured osteoclasts at pOC stages were incubated with or without rmCCL5 for 2 days, and then subjected for RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE106259 | GEO | 2017/11/15

SECONDARY ACCESSION(S): PRJNA416058

REPOSITORIES: GEO

Similar Datasets

2015-04-01 | E-GEOD-45656 | biostudies-arrayexpress
2011-04-29 | E-GEOD-28947 | biostudies-arrayexpress
2019-01-09 | GSE123411 | GEO
2021-09-08 | PXD017245 | Pride
2014-06-02 | E-GEOD-58146 | biostudies-arrayexpress
2010-03-22 | E-GEOD-20850 | biostudies-arrayexpress
2013-07-10 | E-GEOD-48629 | biostudies-arrayexpress
2011-04-29 | E-GEOD-28937 | biostudies-arrayexpress
2013-07-10 | GSE48629 | GEO
2022-11-03 | GSE216929 | GEO