Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Analysis of gene expression levels between RacGAP1 silenced and control SMMC7721 cells

ABSTRACT: To investigate the altered genes by RacGAP1 silencing

ORGANISM(S): Homo sapiens

PROVIDER: GSE108422 | GEO | 2017/12/23

SECONDARY ACCESSION(S): PRJNA427262

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Analysis of gene expression levels between RacGAP1 silenced and control SMMC7721 cells

Project description:Analysis of gene expression levels between RacGAP1 silenced and control SMMC7721 cells

| PRJNA427262 | ENA

Analysis of gene expression levels between CCl4 induced mouse fibrotic liver tissues and vehicle treated mouse control liver tissues.

Project description:To investigate the altered gene expression levels in mouse fibrotic liver tissues, C57BL6/J mice were intraperitoneally injected with CCl4 or vehicle twice every week. After 8 weeks, livers were harvested and RNA was extracted by Trizol. The gene expression levels were analyzed and compared between CCl4 treated group and vehicle treated (control) group.

2015-10-15 | GSE73985 | GEO

Bach1-silenced and control C2C12 cells before and after inducing differentiation

Project description:To investigate the Bach1 function in proliferation and differentiation of myogenic cells, we performed DNA microarray analysis using C2C12 cells with silencing of Bach1 and control cells before and after inducing differentiation.

2020-07-25 | GSE155097 | GEO

RNA-seq analysis of NRF2 silenced human skin fibroblasts

Project description:This RNA-seq analysis was the beginning of our study, to have a first global unbiased approach to analyze the effect of NRF2 silencing on the mRNA profile of human skin fibroblasts. We demonstrated that besides NRF2 conventional antioxidant and metabolic target genes, tissue skeleton and especially matrisome genes were affected by NRF2 silencing. We further confirmed that NRF2 silencing some collagen genes, impacting collagen fibrillogenesis.

2022-06-01 | GSE185129 | GEO

Phagosome proteome of mock and Atg8 silenced Entamoeba histolytica strains

Project description:The enteric protozoan parasite Entamoeba histolytica have high phagocytic ability. Phagocytosis is also important for the pathogenicity of this parasite; molecular mechanisms of phagocytosis and phagosome maturation is focused. Atg8 is well studied autophagy marker protein. We previously shown that E. histolytica Atg8 translocate to nascent trogosomes and expression silencing of the Atg8 caused retardation of phagosome acidification. To investigate how Atg8 regulates phagosome maturation, here we conducted proteome analysis of phagosomes isolated from an E. histolytica strain in which atg8 gene expression are silenced (atg8 gene silenced, atg8-gs) and its mock control strain (transfected with psAP2-Gunma).

2022-10-20 | PXD034376 | Pride

Proteomics study of HDAC6 silenced cells

Project description:The proteomic analysis here introduced was set up and performed to figure out global perturbations of the proteome of a breast cancer human cell line in the presence/absence of HDAC6 silencing.

2024-10-17 | PXD054378 | Pride

RNAseq analysis of lncRNA silenced primary melanoma cell line WM902B

Project description:Purpose: Study the changes in gene expression upon silencing of lncRNA TINCR Methods: Primary melanoma cell line WM902B was transduced with lientiviruses expressing Scrambled and TINCR directed shRNA hairpins Results: we found that TINCR silencing induces switch to invasive phenotype in WM902B primary melanoma cells

2020-11-25 | GSE85656 | GEO

Effect of 4-Hydroxynonenal on gene expression. Comparison of HSF1-siRNA silenced vs control cells

Project description:4-Hydroxynonenal (HNE), a cytotoxic and diffusible electrophile generated by the spontaneous decomposition of oxidized lipids, has a suspected role in neurodegenerative and inflammatory disease processes. In addition to promoting cell death, elevated levels of HNE lead to the engagement of cytoprotective signaling pathways, including the heat shock, antioxidant, DNA damage, and ER stress responses. Activation of the heat shock response, mediated by the transcription factor heat shock factor 1 (HSF1), is critical for maintaining cellular viability in the presence of HNE. Accordingly, silencing HSF1 expression using siRNA enhances the toxicity of HNE. Microarray analysis of samples from control and HSF1-silenced cells was performed to investigate which associated changes in gene could be responsible for the decrease in cellular viability.

2008-10-01 | GSE12762 | GEO