Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut

ABSTRACT: To extend our understanding of bifidobacterial mutualism and carbohydrate syntrophy in the gut we adopted advanced functional genomics to create single- and double-deletion isogenic strains of the NagA encoding genes of B. breve UCC2003. The resulting strains were examined, as compared to the parent strain, for their ability to metabolise particular host derived carbohydrates. In addition, the B. breve strains were examined for their crossfeeding capability and ability to establish, in the presence of B. bifidum ATCC29521, in the gut of dam fed neonatal mice.

ORGANISM(S): Bifidobacterium breve UCC2003

PROVIDER: GSE110077 | GEO | 2018/07/19

REPOSITORIES: GEO