Transcriptomics

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Gene expression profiles of primary samples of acute myeloid leukemia (AML)


ABSTRACT: As part of a clinical trial of the MDM2 inhibitor DS-3032b, 41 primary tumor samples were obtained before treatment from 38 patients newly diagnosed with AML, or relapsed or refractory to standard induction chemotherapy Gene expression features of pretreatment samples, along with TP53 mutation status, were found to correlate with clinical response to DS-3032b (manuscript under review).

ORGANISM(S): Homo sapiens

PROVIDER: GSE110087 | GEO | 2018/05/23

REPOSITORIES: GEO

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