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Expression data from BMDC

ABSTRACT: Dendritic cells increase expression of pro-inflammatory cytokines and chemokines and undergo metabolic reprogramming upon TLR activation. We treated mouse BMDC with TLR7/8 ligand imiquimod (IMQ) and palmitic acid (PA) to reveal inflammatory and metabolic pathways that are sensitive to TLR7/8 activation and a high fatty acid environment. We used microarray to identify pathways in dendritic cells that link inflammation and metabolism in a high fatty acid environment.

ORGANISM(S): Mus musculus

PROVIDER: GSE110962 | GEO | 2019/06/30

REPOSITORIES: GEO

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