Single Cell sequencing of E14.5, E15.5 and E14.5 Kir electroporated cortical neurons.

ABSTRACT: Experimental in vivo hyperpolarization of E14.5 apical progenitors shifted their transcriptional programs with precocious generation of intermediate progenitors, and a forward shift in the laminar, molecular, morphological and circuit features of their neuronal progeny. In particular, we reported an overall repression of L4-type neuronal genes and a premature induction of L2/3-type neuronal genes following Kir2.1 overexpression.

ORGANISM(S): Mus musculus

PROVIDER: GSE115628 | GEO | 2018/06/12

REPOSITORIES: GEO