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Expression data from dissected postnatal 0 (P0) Meg2 (protein-tyrosine phosphatase non-receptor type 9, Ptpn9) knockout and wild-type mouse retinae.

ABSTRACT: In our dataset, we included the expression data obtained from P0 dissected Meg2 knockout and wild-type mouse retinae. Most interestingly, we observed a dysregulation of several candidate genes known to be differentially expressed in response to retinal/glaucomatous neurodegeneration, which includes genes related to apoptosis, excitotoxicity, immune activation, neurotrophic signaling, oxidative stress and loss of synaptic integrity. These data indicate the importance and functional relevance of the protein tyrosine phosphatase Meg2 in retinal integrity and disease.

ORGANISM(S): Mus musculus

PROVIDER: GSE119246 | GEO | 2021/08/30

REPOSITORIES: GEO

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