Transcriptomics

Dataset Information

0

The AML-associated K313 mutation enhances C/EBPα activity by increasing translation via release of ribosome stalling


ABSTRACT: Mutations in the transcription factor C/EBPα are found in about 10% of all acute myeloid leukaemia (AML) cases but the contribution of these mutations to leukaemogenesis is incompletely understood. We here use a mouse model of granulocyte progenitors expressing conditionally active HoxB8 to assess the cell biological and molecular activity of C/EBPα-mutations associated with human AML.

ORGANISM(S): Mus musculus

PROVIDER: GSE120473 | GEO | 2020/05/05

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA493112 | ENA
2013-12-10 | E-GEOD-46534 | biostudies-arrayexpress
2023-11-08 | GSE243423 | GEO
2023-11-08 | GSE243422 | GEO
2013-03-23 | GSE45430 | GEO
2018-04-30 | GSE102730 | GEO
2018-04-30 | GSE102697 | GEO
2013-12-10 | GSE46534 | GEO
2023-04-03 | GSE226423 | GEO
2023-04-03 | GSE226422 | GEO