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PCMV-FAK vs pCMV in HU

ABSTRACT: CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after unloading

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE12745 | GEO | 2009/12/31

SECONDARY ACCESSION(S): PRJNA123159

REPOSITORIES: GEO

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pCMV-FAK vs pCMV in HU

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after unloading paired comparison in contralateral leg

2010-06-24 | E-GEOD-12745 | biostudies-arrayexpress

pCMV-FAK vs pCMV in CTL

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle

2009-12-31 | GSE12743 | GEO

pCMV-FAK vs pCMV in R5

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 5 day of reloading

2009-12-31 | GSE12747 | GEO

pCMV-FAK vs pCMV in R1

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 1 day of reloading

2009-12-31 | GSE12746 | GEO

pCMV-FAK vs pCMV in CTL

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle paired comparison in contralateral leg

2010-06-24 | E-GEOD-12743 | biostudies-arrayexpress

pCMV-FRNK/pCMV-FAK vs pCMV-FAK in CTL

Project description:CMV-driven inhibition of FAK in soleus muscle was compared vs contralateral muscle

2009-12-31 | GSE12744 | GEO

pCMV-FAK vs pCMV in R5

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 5 day of reloading paired comparison in contralateral leg

2009-12-30 | E-GEOD-12747 | biostudies-arrayexpress

pCMV-FAK vs pCMV in R1

Project description:CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 1 day of reloading paired comparison in contralateral leg

2010-06-24 | E-GEOD-12746 | biostudies-arrayexpress

RNA-Seq transcriptome profiling of soleus from adult and aged mice following disuse muscle atrophy and recovery

Project description:Rodent hind limb unloading was used as a model for reduced muscle activity and eventual atrophy. After a 10 day period of unloading, mice in this study were “reloaded” for 3 days and regained use of their hind limbs. We report the application of Next-generation sequencing (NGS) technology for high-throughput profiling of mRNA in soleus muscle of adult (6 mo) and aged (22-24 mo) mice. Our goal was to determine the effects of hind limb unloading and reloading on mRNA profiles in soleus muscle and compare between adult and aged mice. We find that there are distinct response in the profile of fatty acid oxidation, TCA cycle, ETC oxidative phosphorylation gene expression patterns in response to unloading and reloading. The repsonses are generally simialr between young and old mice.

2018-05-15 | GSE102284 | GEO

Skeletal muscle unloading affects muscle progenitor cells functional activity

Project description:In this work we employed classic skeletal muscle unloading rat model to determine how hindlimb suspension (HS) affects functional activity of skeletal muscle progenitor cells (SMPC). We have purified SMPC from m. soleus from control rats and after 1, 3, 7 and 14 days of exposure (HS1, HS3, HS7, HS14).

2022-04-25 | GSE201281 | GEO

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