Transcriptomics

Dataset Information

26

Effect of P. gingivalis on human primary gingival epithelial cells


ABSTRACT: EXPERIMENT: Microarray expression profiles derived from the human primary gingival epithelial cells 24.0h after exposure to heat inactivated P. gingivalis ANIMAL MODEL: NON EXPOSURE: Human primary gingival epithelial cells (at 3rd passage) were exposed to heat inactivated P. gingivalis (MOI:100) at 90% confluence. Two types of gingival epithelial cells were used. One with Normal cytokine inducer type (at least 2 fold IL-6/TNF-alpha/IL-1ß when challenged with TLR2/4 agonists) and the other with diminished cytokine inducer type (no change in IL-6/TNF-alpha/IL-1ß when challenged with TLR2/4 agonists). INTERVAL: NON. PLATFORM: microRNA expression profile in gingival epithelial cells - miRCURY LNA™ microRNA Arrays (Exiqon). The RNA samples were subjected to microarray on 8/9/2007 Keywords = Human primary gingival epithelial cells Keywords = P. gingivalis Keywords = Periodontitis Keywords: Ordered Overall design: The effect of heat inactivated P. gingivalison human primary gingival epithelial cells were assayed.

INSTRUMENT(S): Exiqon miRCURYTM LNA Array Version 8.1

ORGANISM(S): Homo sapiens  

SUBMITTER: Amar Singh  

PROVIDER: GSE13042 | GEO | 2008-11-07

SECONDARY ACCESSION(S): PRJNA109951

REPOSITORIES: GEO

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