Transcriptomics

Dataset Information

0

RNA-seq of triple knockout (TKO) mouse embryonic stem cells: Dnmt1-/-, Dnmt3a-/-, Dnmt3b-/-.

ABSTRACT: TKO mouse embryonic stem cells were cultured in serum/LIF and 2i/LIF in order to investigate the role of methylation in the transcriptional regulation of ground state cells (Clone: TKO 121, Tsumura et.al. 2006).

ORGANISM(S): Mus musculus

PROVIDER: GSE130686 | GEO | 2020/06/19

REPOSITORIES: GEO

Json Xml

Similar Datasets

Genomics RNA-seq of triple knockout (TKO) mouse embryonic stem cells: Dnmt1-/-, Dnmt3a-/-, Dnmt3b-/-.
| PRJNA541006 | ENA
Unknown Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
| S-EPMC4414868 | biostudies-literature
Unknown Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia.
| S-EPMC6509988 | biostudies-literature
Unknown DNMT1, DNMT3A and DNMT3B Polymorphisms Associated With Gastric Cancer Risk: A Systematic Review and Meta-analysis.
| S-EPMC5264435 | biostudies-literature
Unknown DNMT1, DNMT3A and DNMT3B gene variants in relation to ovarian cancer risk in the Polish population.
| S-EPMC3723978 | biostudies-literature
Transcriptomics Expression data from mouse wild-type and Dnmt1-/-Dnmt3a-/-Dnmt3b-/- embryonic stem(ES) cells and nuclear transfer-trophoblastic stem(ntTS) cells, and wild-type trophoblastic stem(TS) cells, primitive endoderm cells, and extra-embryonic endoderm(XEN) cells
2010-09-03 | GSE20177 | GEO
Unknown Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.
| S-EPMC5270636 | biostudies-literature
Transcriptomics RNA-seq analysis of ES cell populations with different functional potentials in serum/LIF and 2i/LIF, as well as analysis of the transcriptional effect of LIF in ground state (2i) culture conditions.
2013-06-11 | GSE45182 | GEO
Methylation profiling Reduced representative bisulfite sequencing (RRBS) analysis for a genome-wide comparison of DNA methylation in wild-type, USP7-KO-1, DNMT3A/3B-DKO and DNMT3A/DNMT3B/USP7-TKO HeLa cell lines.
2020-09-07 | GSE136159 | GEO
Transcriptomics MEK and GSK3β inhibition drives ES cells into a naive pluripotent state irrespective of their global methylation status
2020-06-16 | GSE72302 | GEO