Genomics

Dataset Information

0

Tissue resident macrophages promote renal cystic disease


ABSTRACT: We show that resident macrophages accumulate in cilia mutant mice prior to cyst formation and that inhibition of resident macrophage accumulation reduces cystic kidney disease. Overall design: We analyzed gene expression of R2a (CD11c+) and R2b (CD11c-) resident macrophages isolated from adult, wild type mice. In these experiments, we isolated RNA from 6-8 mice and pooled the RNA together prior to sequencing.

INSTRUMENT(S): Illumina NextSeq 500 (Mus musculus)

ORGANISM(S): Mus musculus  

SUBMITTER: Kurt Zimmerman  

PROVIDER: GSE131896 | GEO | 2019-07-04

REPOSITORIES: GEO

Dataset's files

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Action DRS
GSE131896_raw_counts.xlsx Xlsx
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