Single cell RNA sequencing analysis of CD8+ T cell subsets following DENV-vaccine administration

ABSTRACT: PBMC-derived CD8 T cell activation and gene expression profiles were assessed 14 days following a single dose of a candidate live-attenuated tetravalent denge virus vaccine (DENVax). Three distinct populations of CD8+ T cells were isolated by flow cytometric sorting: 1) CD3+ CD8+ CD38- HLA-DR- T cells, 2) CD3+ CD8+ CD38+ HLA-DR+ T cells, and 3) CD3+ CD8+ CD71+ HLA-DR+ T cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE132950 | GEO | 2019/08/05

REPOSITORIES: GEO