EXP_139_AC_ranscriptional changes observed in 94T778 cells subjected to different pharmacologic pressures.
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ABSTRACT: 94T778 cells were exposed to nutlin-3a, palbociclib and tunicamycin. Cells were harvested during the early phase of the adaptive evolution in 94T778 cells exposed to palbociclib (P), nutlin-3a (N) and tunicamycin (T) sampled at 10 weeks for P and N and at 9 weeks post-bottleneck for T condition. Overall design: The experiment was designed to study the impact of targeted anti-cancer therapies on the expression of genes involed in different DNA repair pathways
INSTRUMENT(S): Illumina HiSeq 2500 (Homo sapiens)
ORGANISM(S): Homo sapiens
SUBMITTER:
David Goode
PROVIDER: GSE148342 | GEO | 2020-04-09
REPOSITORIES: GEO
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