Transcriptomics

Dataset Information

35

Hormone effects on gene expression in somatic cells of rat testes (Rattus norvegicus)


ABSTRACT: Analysis of hormone effects on irradiated LBNF1 rat testes, which contain only somatic cells except for a few type A spermatgogonia. Rats were treated for 2 weeks with either sham treatment (group X), hormonal ablation (GnRH antagonist and the androgen receptor antagonist flutamide, group XAF), testosterone supplementation (GnRH antagonist and testosterone, group XAT), and FSH supplementation ((GnRH antagonist, androgen receptor antagonist, and FSH, group XAFF). Results provide insight into identifying genes in the somatic testis cells regulated by testosterone, LH, or FSH. Overall design: 14 Sample replicates of sham treatment, 11 Sample replicates of hormonal ablation, 5 Sample replicates of testosterone supplementation, and 5 Sample replicates of FSH supplementation were studied.

INSTRUMENT(S): [Rat230_2] Affymetrix Rat Genome 230 2.0 Array

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Wei Zhou  

PROVIDER: GSE15243 | GEO | 2009-09-30

SECONDARY ACCESSION(S): PRJNA116529

REPOSITORIES: GEO

Similar Datasets

2009-10-10 | E-GEOD-15243 | ArrayExpress
2013-11-22 | BIOMD0000000494 | BioModels
2014-02-25 | E-GEOD-44664 | ArrayExpress
2011-11-22 | GSE24672 | GEO
2011-11-22 | E-GEOD-24672 | ArrayExpress
2009-09-01 | GSE16030 | GEO
2009-09-01 | E-GEOD-16030 | ArrayExpress
| GSE57937 | GEO
2010-12-21 | E-GEOD-19959 | ArrayExpress
2010-09-06 | E-GEOD-18140 | ArrayExpress