Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of ADGRF4 knockdown on gene expression pattern in A549 cells

ABSTRACT: A549 human lung cancer cells were knocked down with either siControl or siADGRF4. Gene expression levels were analyzed by RNA sequencing. ADGRF4 globally altered expression patterns of genes in A549 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE153554 | GEO | 2020/07/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-seq analysis using A549 cells with TRIM22 knockdown and control A549 cells with or without ionizing radiation treatment.

Project description:In this study, we explored the role of TRIM22 in the response to ionizing radiation (IR) in A549 human lung cancer cells. TRIM22 was stably knocked down in A549 cells using shRNA, and four experimental groups were established: control A549 cells (non-irradiated), control A549 cells (irradiated), TRIM22 knockdown A549 cells (non-irradiated), and TRIM22 knockdown A549 cells (irradiated). RNA sequencing (RNA-seq) was performed to identify gene expression changes associated with TRIM22 knockdown and irradiation. This dataset provides insights into the molecular mechanisms by which TRIM22 influences the cellular response to radiation and its potential impact on cancer therapy.

2025-01-01 | GSE277805 | GEO

RNA-seq analysis using A549 cells with FXR knockdown and control A549 cells with or without ionizing radiation treatment.

Project description:In this study, we explored the role of FXR in the response to ionizing radiation (IR) in A549 human lung cancer cells. FXR was stably knocked down in A549 cells using shRNA, and four experimental groups were established: control A549 cells (non-irradiated), control A549 cells (irradiated), FXR knockdown A549 cells (non-irradiated), and FXR knockdown A549 cells (irradiated). RNA sequencing (RNA-seq) was performed to identify gene expression changes associated with FXR knockdown and irradiation. This dataset provides insights into the molecular mechanisms by which FXR influences the cellular response to radiation and its potential impact on cancer therapy.

2024-10-31 | GSE278872 | GEO

Tandem mass tag-mass spectrometry of CCT3 knockdown A549 and H1299 cell lines

Project description:CCT3 was knocked down in H1299 and A549 cell lines. TMT-MS was employed to detect the differences of intracellular proteins abundance.

2022-03-11 | PXD032248 |

Knockdown TIMM13 in A549 lung cancer cell line

Project description:We depleted TIMM13 using short interfering RNA (siRNA) in A549 lung cancer cells, and found that silencing of TIMM13 could significantly inhibit A549 cell proliferation. Thus, we conducted RNA-seq in the A549 cells transduced with either nontargeting siRNA or two distinct TIMM13-specific siRNAs. We observed widespread gene expression change in A549 cells upon TIMM13 knockdown.

2023-06-17 | GSE234780 | GEO

Analysis of NRF2 knockdown effect in A549 and H1437 cells

Project description:This project tessts whether translation of all selenoproteins are affected by NRF2 downregualation in A549 and H1437 cells.

2020-10-22 | PXD018634 | Pride

Effect of ADGRF4 knockdown on gene expression pattern in A549 cells

Project description:Effect of ADGRF4 knockdown on gene expression pattern in A549 cells

| PRJNA643228 | ENA

RNPC3 knockdown in A549 lung adenocarcinoma cells

Project description:RNPC3 knockdown in A549 lung adenocarcinoma cells

| PRJNA789044 | ENA

Transcriptomic analysis of RNases knockdown in A549 cells.

Project description:The function of biomolecules is essential for maintaining homeostasis. The RNA and RNase regulatory system in maintaining cellular homeostasis is not clear. To investigate the effects of RNase on gene expression and biological functions, we respectively knocked down Ago2, ANG, DICER, DROSHA, RNase L, and RNase T2 in A549 cells and performed RNA sequencing.

2024-08-01 | GSE211711 | GEO

Gene expression profiles of PML knockdown or WDR4 overexpression in A549 cells

Project description:Lung cancer cell line, A549 cells, was transfected with siPML or siCtrl for 48hr to knockdown PML expression. WDR4 or vector was overexpressed in A549 cells for 48hr. These four sets of cells were then subjected to microarray profiling using the Human OneArray microarray (version HOA6.1, GEO Platform GPL19137) from Phalanx Biotech Group. Comparison of transcriptomes from siPML/siCtrl and W4/vec in A549 cells

2016-07-04 | E-GEOD-83499 | biostudies-arrayexpress

Human lung cancer cell line A549 +/- CD43 knockdown

Project description:Human lung cancer cell line A549 +/- CD43 knockdown

| PRJNA749458 | ENA